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Exacerbation of gout following therapy with probenecid and colchicine may occur; in such cases additional colchicine or other appropriate therapy is advisable.
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When colchicine is used to relieve the pain of a gout attack, one dose is usually taken at the first sign of pain and a second, smaller dose is usually taken one hour later.
Examples of affected drugs include asunaprevir, colchicine, flibanserin, ivabradine, lomitapide, midazolam, triazolam, among others.
Colchicine may also be used for purposes not listed in this medication guide.
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colchicine was the primary treatment for a rare inflammatory disease called familial mediterranean fever but for years was sold at very low cost and widely used to treat gout.